20
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15942 | MK-7622 | M1 receptor modulator | AChR |
MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric. | |||
T81893 | M1/M4 muscarinic agonist 2 | ||
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1]. | |||
T9353 | OXOMEMAZINE | AChR , Histamine Receptor | |
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ... | |||
T7002 | Trihexyphenidyl hydrochloride | Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride | AChR |
Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class. | |||
TN1653 | Fustin | ERK , Beta Amyloid , AChR | |
Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death. | |||
T23297 | (S)-(+)-Dimethindene maleate | AChR , Histamine Receptor | |
(S)-(+)-Dimethindene maleate is an orally available, selective muscarinic M2 receptor and histamine H1 receptor antagonist that inhibits muscarinic M1, M3, and M4 receptors. | |||
T80662 | CDD0102 HCl | CDD0102A HCl | AChR |
CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease. | |||
T22963 | McN-A 343 | AChR | |
McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ... | |||
T68153 | Tazomeline | AChR | |
Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity. | |||
T23071 | Nitrocaramiphen hydrochloride | AChR | |
M1 muscarinic antagonist | |||
T23508 | VU 0255035 | AChR | |
muscarinic M1 antagonist | |||
T1542 | Pirenzepine dihydrochloride | Pirenzepine HCl,Bisvanil,Tabe,LS519 | AChR |
Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion. | |||
T12531 | PQCA | Others , AChR | |
PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and 135 nM in human M1 receptors, but showed no activity again... | |||
T8147 | Solifenacin | YM905 free base | AChR |
Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0, respectively. | |||
T4727 | Taurolithocholic acid sodium salt | Sodium taurolithocholate | Others , Calcium Channel |
Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors. | |||
T20026 | WEB-1868 | WEB 1868,WEB1868 | Others |
WEB-1868 is one of the metabolites of nebracetam which is an agonist for human M1-muscarinic receptors. | |||
T8224 | VU0119498 | AChR | |
VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent. | |||
T7780 | Blarcamesine | AE-37,AVex-73 | AChR |
Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease. | |||
T12201 | Nebracetam hydrochloride | WEB 1881 FU hydrochloride | AChR |
Nebracetam hydrochloride (WEB 1881 FU hydrochloride) is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 m... | |||
T8383 | Cyclopentolate Hydrochloride | AChR | |
Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively. |