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Search Results for " muscarinic m1 "

20

Compounds

Cat No. Product Name Synonyms Targets
T15942 MK-7622 M1 receptor modulator AChR
MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.
T81893 M1/M4 muscarinic agonist 2
Compound 40 is a selective M1/M4 muscarinic antagonist with an IC50 of 19 nM for M1 receptors and 42 nM for M4 receptors [1].
T9353 OXOMEMAZINE AChR , Histamine Receptor
Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ...
T7002 Trihexyphenidyl hydrochloride Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride AChR
Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class.
TN1653 Fustin ERK , Beta Amyloid , AChR
Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death.
T23297 (S)-(+)-Dimethindene maleate AChR , Histamine Receptor
(S)-(+)-Dimethindene maleate is an orally available, selective muscarinic M2 receptor and histamine H1 receptor antagonist that inhibits muscarinic M1, M3, and M4 receptors.
T80662 CDD0102 HCl CDD0102A HCl AChR
CDD0102 HCl is a selective and potent M1 muscarinic receptor agonist for the treatment of Alzheimer's disease.
T22963 McN-A 343 AChR
McN-A 343 is a selective M1 muscarinic agonist known for its ability to stimulate muscarinic transmission in sympathetic ganglia. It has been found to effectively reduce inflammation and oxidative stress in experimental ...
T68153 Tazomeline AChR
Tazomeline is a muscarinic M1 receptor agonist with neuroprotective activity.
T23071 Nitrocaramiphen hydrochloride AChR
M1 muscarinic antagonist
T23508 VU 0255035 AChR
muscarinic M1 antagonist
T1542 Pirenzepine dihydrochloride Pirenzepine HCl,Bisvanil,Tabe,LS519 AChR
Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion.
T12531 PQCA Others , AChR
PQCA is a muscarinic M1 receptor-positive allosteric regulator, which is highly selective and effective. PQCA exhibited EC50 values of 49 nM in rhesus monkey and 135 nM in human M1 receptors, but showed no activity again...
T8147 Solifenacin YM905 free base AChR
Solifenacin (YM905 free base) (YM905 free base) is a novel muscarinic receptor antagonist, its pKis for M1, M2 and M3 receptors is of 7.6, 6.9 and 8.0, respectively.
T4727 Taurolithocholic acid sodium salt Sodium taurolithocholate Others , Calcium Channel
Taurolithocholic acid sodium salt (Sodium taurolithocholate) is the major human metabolite, a bile acid which inhibits radioligand binding to muscarinic M1, but not to M2 or M3 receptors.
T20026 WEB-1868 WEB 1868,WEB1868 Others
WEB-1868 is one of the metabolites of nebracetam which is an agonist for human M1-muscarinic receptors.
T8224 VU0119498 AChR
VU0119498 is a M1 muscarinic receptor agonist (EC50 = 3.1 μM) and pan mAChR M3, M5 positive allosteric modulator (PAM),and is a neuroprotective agent.
T7780 Blarcamesine AE-37,AVex-73 AChR
Blarcamesine (AVex-73) is a muscarinic M1 agonist potentially for the treatment of Alzheimer's disease.
T12201 Nebracetam hydrochloride WEB 1881 FU hydrochloride AChR
Nebracetam hydrochloride (WEB 1881 FU hydrochloride) is an agonist nootropic M1-muscarinic. Nebracetam hydrochloride induces a rise of intracellular Ca2+ concentration. Nebracetam hydrochloride exhibits an EC50 of 1.59 m...
T8383 Cyclopentolate Hydrochloride AChR
Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.
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TargetMol